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Targeting Human α-Lactalbumin Gene Insertion into the Goat β-Lactoglobulin Locus by TALEN-Mediated Homologous Recombination

Special value of goat milk in human nutrition and well being is associated with medical problems of food allergies which are caused by milk proteins such as β-lactoglobulin (BLG). Here, we employed transcription activator-like effector nuclease (TALEN)-assisted homologous recombination in goat fibro...

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Detalles Bibliográficos
Autores principales: Zhu, Hongmei, Liu, Jun, Cui, Chenchen, Song, Yujie, Ge, Hengtao, Hu, Linyong, Li, Qian, Jin, Yaping, Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892491/
https://www.ncbi.nlm.nih.gov/pubmed/27258157
http://dx.doi.org/10.1371/journal.pone.0156636