Cargando…

Dual Role of the Tyrosine Kinase Syk in Regulation of Toll-Like Receptor Signaling in Plasmacytoid Dendritic Cells

Crosslinking of regulatory immunoreceptors (RR), such as BDCA-2 (CD303) or ILT7 (CD85g), of plasmacytoid dendritic cells (pDCs) efficiently suppresses production of type-I interferon (IFN)-α/β and other cytokines in response to Toll-like receptor (TLR) 7/9 ligands. This cytokine-inhibitory pathway i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Aouar, Besma, Kovarova, Denisa, Letard, Sebastien, Font-Haro, Albert, Florentin, Jonathan, Weber, Jan, Durantel, David, Chaperot, Laurence, Plumas, Joel, Trejbalova, Katerina, Hejnar, Jiri, Nunès, Jacques A., Olive, Daniel, Dubreuil, Patrice, Hirsch, Ivan, Stranska, Ruzena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892542/ https://www.ncbi.nlm.nih.gov/pubmed/27258042 http://dx.doi.org/10.1371/journal.pone.0156063

Ejemplares similares

The MEK1/2-ERK Pathway Inhibits Type I IFN Production in Plasmacytoid Dendritic Cells
por: Janovec, Vaclav, et al.
Publicado: (2018)

Hepatitis C virus fails to activate NF-kappaB signaling in plasmacytoid dendritic cells
por: Stranska, Ruzena, et al.
Publicado: (2012)

DNA hypomethylation and aberrant expression of the human endogenous retrovirus ERVWE1/syncytin-1 in seminomas
por: Benešová, Martina, et al.
Publicado: (2017)

Development of 5‘ LTR DNA methylation of latent HIV-1 provirus in cell line models and in long-term-infected individuals
por: Trejbalová, Kateřina, et al.
Publicado: (2016)

Expression of TIM-3 on Plasmacytoid Dendritic Cells as a Predictive Biomarker of Decline in HIV-1 RNA Level during ART
por: Font-Haro, Albert, et al.
Publicado: (2018)

Cross Talk between Inhibitory Immunoreceptor Tyrosine-Based Activation Motif-Signaling and Toll-Like Receptor Pathways in Macrophages and Dendritic Cells
por: Hirsch, Ivan, et al.
Publicado: (2017)

Highly efficient transduction of human plasmacytoid dendritic cells without phenotypic and functional maturation
por: Veron, Philippe, et al.
Publicado: (2009)

Plasmacytoid Dendritic Cells Capture and Cross-Present Viral Antigens from Influenza-Virus Exposed Cells
por: Lui, Gabrielle, et al.
Publicado: (2009)

Characterization of species-specific genes regulated by E2-2 in human plasmacytoid dendritic cells
por: Cheng, Menglan, et al.
Publicado: (2015)

A Novel Cancer Vaccine Strategy Based on HLA-A*0201 Matched Allogeneic Plasmacytoid Dendritic Cells
por: Aspord, Caroline, et al.
Publicado: (2010)

P16-52. HIV-activated human plasmacytoid DCs induce Tregs through an indoleamine 2,3-dioxygenase-dependent mechanism
por: Manches, O, et al.
Publicado: (2009)

Engineering a Human Plasmacytoid Dendritic Cell-Based Vaccine to Prime and Expand Multispecific Viral and Tumor Antigen-Specific T-Cells
por: Lenogue, Kevin, et al.
Publicado: (2021)

NFATC3 promotes IRF7 transcriptional activity in plasmacytoid dendritic cells
por: Bao, Musheng, et al.
Publicado: (2016)

Death receptor 6 is a novel plasmacytoid dendritic cell-specific receptor and modulates type I interferon production
por: Li, Jingyun, et al.
Publicado: (2016)

Melanoma hijacks plasmacytoid dendritic cells to promote its own progression
por: Aspord, Caroline, et al.
Publicado: (2014)

CpG methylation controls reactivation of HIV from latency
por: Blazkova, Jana, et al.
Publicado: (2010)

HIV Delays IFN-α Production from Human Plasmacytoid Dendritic Cells and Is Associated with SYK Phosphorylation
por: Lo, Calvin C., et al.
Publicado: (2012)

A New Plasmacytoid Dendritic Cell-Based Vaccine in Combination with Anti-PD-1 Expands the Tumor-Specific CD8+ T Cells of Lung Cancer Patients
por: Hannani, Dalil, et al.
Publicado: (2023)

CpG Methylation Controls Reactivation of HIV from Latency
por: Blazkova, Jana, et al.
Publicado: (2009)

The epigenetic control of HERV loci encoding for fusogenic envelope glycoproteins in trophoblast
por: Blazkova, Jana, et al.
Publicado: (2009)

Highjacking of PI3K/AKT signaling pathway by Hepatitis C virus in TLR9-activated human plasmacytoid dendritic cells
por: Florentin, Jonathan, et al.
Publicado: (2010)

Epigenetic regulation of transcription and splicing of syncytins, fusogenic glycoproteins of retroviral origin
por: Trejbalová, Kateřina, et al.
Publicado: (2011)

HIV triggers immunoregulatory dendritic cells and regulatory T cells through the non-canonical NF-kB pathway
por: Manches, O, et al.
Publicado: (2012)

Leveraging a powerful allogeneic dendritic cell line towards neoantigen-based cancer vaccines
por: Hannani, Dalil, et al.
Publicado: (2023)

Toll‐like receptors matter: plasmacytoid dendritic cells in COVID‐19
por: Becker, Jennifer, et al.
Publicado: (2022)

An innovative plasmacytoid dendritic cell line-based cancer vaccine primes and expands antitumor T-cells in melanoma patients in a first-in-human trial
por: Charles, Julie, et al.
Publicado: (2020)

The Syk-Coupled C-Type Lectin Receptors Dectin-2 and Dectin-3 Are Involved in Paracoccidioides brasiliensis Recognition by Human Plasmacytoid Dendritic Cells
por: Preite, Nycolas Willian, et al.
Publicado: (2018)

Syk kinase is required for collaborative cytokine production induced through Dectin-1 and Toll-like receptors
por: Dennehy, Kevin M, et al.
Publicado: (2008)

Potent Bidirectional Cross-Talk Between Plasmacytoid Dendritic Cells and γδT Cells Through BTN3A, Type I/II IFNs and Immune Checkpoints
por: Girard, Pauline, et al.
Publicado: (2020)

Properties regulating the nature of the plasmacytoid dendritic cell response to Toll-like receptor 9 activation
por: Guiducci, Cristiana, et al.
Publicado: (2006)

Identification of Toll-Like Receptor 9 as Parapoxvirus Ovis-Sensing Receptor in Plasmacytoid Dendritic Cells
por: von Buttlar, Heiner, et al.
Publicado: (2014)

SYK Allelic Loss and the Role of Syk-Regulated Genes in Breast Cancer Survival
por: Blancato, Jan, et al.
Publicado: (2014)

The transmembrane adapter SCIMP recruits tyrosine kinase Syk to phosphorylate Toll-like receptors to mediate selective inflammatory outputs
por: Liu, Liping, et al.
Publicado: (2022)

Toll-like Receptor 9–mediated Recognition of Herpes Simplex Virus-2 by Plasmacytoid Dendritic Cells
por: Lund, Jennifer, et al.
Publicado: (2003)

Cidofovir is active against human papillomavirus positive and negative head and neck and cervical tumor cells by causing DNA damage as one of its working mechanisms
por: Mertens, Barbara, et al.
Publicado: (2016)

Photopheresis efficacy in the treatment of rheumatoid arthritis: a pre-clinical proof of concept
por: Coppard, Céline, et al.
Publicado: (2019)

Heterologous avian system for quantitative analysis of Syncytin-1 interaction with ASCT2 receptor
por: Štafl, Kryštof, et al.
Publicado: (2021)

Get Syk and get cycling
por: Williams, Ruth
Publicado: (2006)

Syk and Yea Shall Find
por: Wolozin, Benjamin, et al.
Publicado: (2015)

Hepatitis C Virus Is a Weak Inducer of Interferon Alpha in Plasmacytoid Dendritic Cells in Comparison with Influenza and Human Herpesvirus Type-1
por: Gondois-Rey, Françoise, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_ergfjget4lnndavqt254thqsf7