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Graded effects of unregulated smooth muscle myosin on intestinal architecture, intestinal motility and vascular function in zebrafish

Smooth muscle contraction is controlled by the regulated activity of the myosin heavy chain ATPase (Myh11). Myh11 mutations have diverse effects in the cardiovascular, digestive and genitourinary systems in humans and animal models. We previously reported a recessive missense mutation, meltdown (mlt...

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Detalles Bibliográficos
Autores principales: Abrams, Joshua, Einhorn, Zev, Seiler, Christoph, Zong, Alan B., Sweeney, H. Lee, Pack, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892660/
https://www.ncbi.nlm.nih.gov/pubmed/26893369
http://dx.doi.org/10.1242/dmm.023309

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