A novel inhibitor of p75-neurotrophin receptor improves functional outcomes in two models of traumatic brain injury

The p75 neurotrophin receptor is important in multiple physiological actions including neuronal survival and neurite outgrowth during development, and after central nervous system injury. We have discovered a novel piperazine-derived compound, EVT901, which interferes with p75 neurotrophin receptor...

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Detalles Bibliográficos
Autores principales: Delbary-Gossart, Sandrine, Lee, Sangmi, Baroni, Marco, Lamarche, Isabelle, Arnone, Michele, Canolle, Benoit, Lin, Amity, Sacramento, Jeffrey, Salegio, Ernesto A., Castel, Marie-Noelle, Delesque-Touchard, Nathalie, Alam, Antoine, Laboudie, Patricia, Ferzaz, Badia, Savi, Pierre, Herbert, Jean-Marc, Manley, Geoffrey T., Ferguson, Adam R., Bresnahan, Jacqueline C., Bono, Françoise, Beattie, Michael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892754/
https://www.ncbi.nlm.nih.gov/pubmed/27084575
http://dx.doi.org/10.1093/brain/aww074

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