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Anti-EGFR-iRGD recombinant protein conjugated silk fibroin nanoparticles for enhanced tumor targeting and antitumor efficiency

In this study, we report a novel kind of targeting with paclitaxel (PTX)-loaded silk fibroin nanoparticles conjugated with iRGD–EGFR nanobody recombinant protein (anti-EGFR-iRGD). The new nanoparticles (called A-PTX-SF-NPs) were prepared using the carbodiimide-mediated coupling procedure and their c...

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Detalles Bibliográficos
Autores principales:	Bian, Xinyu, Wu, Puyuan, Sha, Huizi, Qian, Hanqing, Wang, Qing, Cheng, Lei, Yang, Yang, Yang, Mi, Liu, Baorui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2016
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892850/ https://www.ncbi.nlm.nih.gov/pubmed/27313461 http://dx.doi.org/10.2147/OTT.S100678

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