Cargando…

Isoproterenol increases histone deacetylase 6 expression and cell migration by inhibiting ERK signaling via PKA and Epac pathways in human lung cancer cells

Stress conditions are correlated with tumor growth, progression and metastasis. We hypothesized that stress signals might affect tumor progression via epigenetic control of gene expression and investigated the effects of stress signals on the expression levels of histone deacetylases (HDACs) and the...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lim, Jeong Ah, Juhnn, Yong-Sung
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892858/ https://www.ncbi.nlm.nih.gov/pubmed/27534532 http://dx.doi.org/10.1038/emm.2015.98

Ejemplares similares

cAMP signaling increases histone deacetylase 8 expression via the Epac2–Rap1A–Akt pathway in H1299 lung cancer cells
por: Park, Ji-Yeon, et al.
Publicado: (2017)

PKA and Epac synergistically inhibit smooth muscle cell proliferation
por: Hewer, Richard C., et al.
Publicado: (2011)

cAMP inhibits migration, ruffling and paxillin accumulation in focal adhesions of pancreatic ductal adenocarcinoma cells: Effects of PKA and EPAC()
por: Burdyga, Alex, et al.
Publicado: (2013)

MicroRNA-489 suppresses isoproterenol-induced cardiac fibrosis by downregulating histone deacetylase 2
por: Yang, Xiaoyu, et al.
Publicado: (2020)

Opposing Roles of pka and epac in the cAMP-Dependent Regulation of Schwann Cell Proliferation and Differentiation
por: Bacallao, Ketty, et al.
Publicado: (2013)

cAMP Signaling in Cancer: A PKA-CREB and EPAC-Centric Approach
por: Ahmed, Muhammad Bilal, et al.
Publicado: (2022)

Correction: Opposing Roles of pka and epac in the cAMP-Dependent Regulation of Schwann Cell Proliferation and Differentiation
por: Bacallao, Ketty, et al.
Publicado: (2014)

Epac1 and PKA agonists inhibit ROS to reduce NLRP3 inflammasome proteins in retinal endothelial cells
por: Liu, Li, et al.
Publicado: (2022)

Histone deacetylase 6 in cancer
por: Li, Ting, et al.
Publicado: (2018)

Histone Deacetylase Inhibitor Treatment Increases the Expression of the Plasma Membrane Ca(2+) Pump PMCA4b and Inhibits the Migration of Melanoma Cells Independent of ERK
por: Hegedüs, Luca, et al.
Publicado: (2017)

PKA and Epac cooperate to augment bradykinin-induced interleukin-8 release from human airway smooth muscle cells
por: Roscioni, Sara S, et al.
Publicado: (2009)

Epac inhibits migration and proliferation of human prostate carcinoma cells
por: Grandoch, M, et al.
Publicado: (2009)

Histone Deacetylases and Histone Deacetylase Inhibitors in Neuroblastoma
por: Phimmachanh, Monica, et al.
Publicado: (2020)

Requirement of Histone Deacetylase 6 for Interleukin-6 Induced Epithelial-Mesenchymal Transition, Proliferation, and Migration of Peritoneal Mesothelial Cells
por: Shi, Yingfeng, et al.
Publicado: (2021)

Anti-Inflammatory Role of the cAMP Effectors Epac and PKA: Implications in Chronic Obstructive Pulmonary Disease
por: Oldenburger, Anouk, et al.
Publicado: (2012)

Glucagon Stimulates Hepatic FGF21 Secretion through a PKA- and EPAC-Dependent Posttranscriptional Mechanism
por: Cyphert, Holly A., et al.
Publicado: (2014)

PKA and Epac1 Reduce Nek7 to Block the NLRP3 Inflammasome Proteins in the Retinal Vasculature
por: Liu, Li, et al.
Publicado: (2022)

Cardioprotection of Immature Heart by Simultaneous Activation of PKA and Epac: A Role for the Mitochondrial Permeability Transition Pore
por: Lewis, Martin John, et al.
Publicado: (2022)

Dysferlin Interacts with Histone Deacetylase 6 and Increases alpha-Tubulin Acetylation
por: Di Fulvio, Sabrina, et al.
Publicado: (2011)

Epac1 increases migration of endothelial cells and melanoma cells via FGF2-mediated paracrine signaling
por: Baljinnyam, Erdene, et al.
Publicado: (2014)

Regulation of cellular contractile force, shape and migration of fibroblasts by oncogenes and Histone deacetylase 6
por: López-Guajardo, Ana, et al.
Publicado: (2023)

Gβγ subunits inhibit Epac-induced melanoma cell migration
por: Baljinnyam, Erdene, et al.
Publicado: (2011)

Histone deacetylase-4 and histone deacetylase-8 regulate interleukin-1β-induced cartilage catabolic degradation through MAPK/JNK and ERK pathways
por: Wang, Pengcheng, et al.
Publicado: (2018)

Histone deacetylase 9 regulates breast cancer cell proliferation and the response to histone deacetylase inhibitors
por: Lapierre, Marion, et al.
Publicado: (2016)

Both PKA and Epac Pathways Mediate N-Acetylcysteine-Induced Connexin43 Preservation in Rats with Myocardial Infarction
por: Lee, Tsung-Ming, et al.
Publicado: (2013)

Catecholamines facilitate VEGF-dependent angiogenesis via β(2)-adrenoceptor-induced Epac1 and PKA activation
por: Garg, Jaspal, et al.
Publicado: (2017)

Histone deacetylase 6 activity is critical for the metastasis of Burkitt’s lymphoma cells
por: Ding, Ning, et al.
Publicado: (2014)

Retraction: Dysferlin Interacts with Histone Deacetylase 6 and Increases alpha-Tubulin Acetylation
Publicado: (2018)

Histone deacetylase 3 promotes alveolar epithelial–mesenchymal transition and fibroblast migration under hypoxic conditions
por: Jeong, Sung Hwan, et al.
Publicado: (2022)

Histone deacetylase 6 is overexpressed and promotes tumor growth of colon cancer through regulation of the MAPK/ERK signal pathway
por: Zhang, Shi-Lan, et al.
Publicado: (2019)

Activation of β-Adrenoceptors Promotes Lipid Droplet Accumulation in MCF-7 Breast Cancer Cells via cAMP/PKA/EPAC Pathways
por: Silva, Dany, et al.
Publicado: (2023)

Monoamine Oxidase-B Inhibitor Reduction in Pro-Inflammatory Cytokines Mediated by Inhibition of cAMP-PKA/EPAC Signaling
por: Putnins, Edward E., et al.
Publicado: (2021)

Beyond Histone and Deacetylase: An Overview of Cytoplasmic Histone Deacetylases and Their Nonhistone Substrates
por: Yao, Ya-Li, et al.
Publicado: (2011)

Selectivity of Hydroxamate- and Difluoromethyloxadiazole-Based Inhibitors of Histone Deacetylase 6 In Vitro and in Cells
por: Ptacek, Jakub, et al.
Publicado: (2023)

Role of Histone Deacetylases in T-Cell Development and Function
por: Pieniawska, Monika, et al.
Publicado: (2022)

Statins and Histone Deacetylase Inhibitors Affect Lamin A/C – Histone Deacetylase 2 Interaction in Human Cells
por: Mattioli, Elisabetta, et al.
Publicado: (2019)

Histone Deacetylase Expressions in Hepatocellular Carcinoma and Functional Effects of Histone Deacetylase Inhibitors on Liver Cancer Cells In Vitro
por: Freese, Kim, et al.
Publicado: (2019)

Targeted inhibition of histone deacetylase 6 in inflammatory diseases
por: Ran, Jie, et al.
Publicado: (2019)

Histone Deacetylase 6 and the Disease Mechanisms of α-Synucleinopathies
por: Lemos, Miguel, et al.
Publicado: (2020)

The Set3/Hos2 Histone Deacetylase Complex Attenuates cAMP/PKA Signaling to Regulate Morphogenesis and Virulence of Candida albicans
por: Hnisz, Denes, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_eor6d47efm9fh6gtsn91t3vccg