Cargando…

Myeloid deletion of SIRT1 suppresses collagen-induced arthritis in mice by modulating dendritic cell maturation

The type III histone deacetylase silent information regulator 1 (SIRT1) is an enzyme that is critical for the modulation of immune and inflammatory responses. However, the data on its role in rheumatoid arthritis (RA) are limited and controversial. To better understand how SIRT1 regulates adaptive i...

Descripción completa

Detalles Bibliográficos
Autores principales: Woo, Seong Ji, Lee, Sang-Myeong, Lim, Hye Song, Hah, Young-Sool, Jung, In Duk, Park, Yeong-Min, Kim, Hyun-Ok, Cheon, Yun-Hong, Jeon, Min-Gyu, Jang, Kyu Yun, Kim, Kyeong Min, Park, Byung-Hyun, Lee, Sang-Il
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892877/
https://www.ncbi.nlm.nih.gov/pubmed/26987484
http://dx.doi.org/10.1038/emm.2015.124