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Myeloid deletion of SIRT1 suppresses collagen-induced arthritis in mice by modulating dendritic cell maturation
The type III histone deacetylase silent information regulator 1 (SIRT1) is an enzyme that is critical for the modulation of immune and inflammatory responses. However, the data on its role in rheumatoid arthritis (RA) are limited and controversial. To better understand how SIRT1 regulates adaptive i...
Autores principales: | Woo, Seong Ji, Lee, Sang-Myeong, Lim, Hye Song, Hah, Young-Sool, Jung, In Duk, Park, Yeong-Min, Kim, Hyun-Ok, Cheon, Yun-Hong, Jeon, Min-Gyu, Jang, Kyu Yun, Kim, Kyeong Min, Park, Byung-Hyun, Lee, Sang-Il |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4892877/ https://www.ncbi.nlm.nih.gov/pubmed/26987484 http://dx.doi.org/10.1038/emm.2015.124 |
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