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Production of small RNAs by mammalian Dicer
MicroRNA (miRNA) and RNA interference (RNAi) pathways employ RNase III Dicer for the biogenesis of small RNAs guiding post-transcriptional repression. Requirements for Dicer activity differ in the two pathways. The biogenesis of miRNAs requires a single Dicer cleavage of a short hairpin precursor to...
Autores principales: | Svobodova, Eliska, Kubikova, Jana, Svoboda, Petr |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893058/ https://www.ncbi.nlm.nih.gov/pubmed/27048428 http://dx.doi.org/10.1007/s00424-016-1817-6 |
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