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Production of small RNAs by mammalian Dicer

MicroRNA (miRNA) and RNA interference (RNAi) pathways employ RNase III Dicer for the biogenesis of small RNAs guiding post-transcriptional repression. Requirements for Dicer activity differ in the two pathways. The biogenesis of miRNAs requires a single Dicer cleavage of a short hairpin precursor to...

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Detalles Bibliográficos
Autores principales: Svobodova, Eliska, Kubikova, Jana, Svoboda, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893058/
https://www.ncbi.nlm.nih.gov/pubmed/27048428
http://dx.doi.org/10.1007/s00424-016-1817-6

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