TLR-independent anti-inflammatory function of intestinal epithelial TRAF6 signalling prevents DSS-induced colitis in mice

OBJECTIVE: The gut microbiota modulates host susceptibility to intestinal inflammation, but the cell types and the signalling pathways orchestrating this bacterial regulation of intestinal homeostasis remain poorly understood. Here, we investigated the function of intestinal epithelial toll-like rec...

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Detalles Bibliográficos
Autores principales: Vlantis, Katerina, Polykratis, Apostolos, Welz, Patrick-Simon, van Loo, Geert, Pasparakis, Manolis, Wullaert, Andy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Experimental Colitis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893119/
https://www.ncbi.nlm.nih.gov/pubmed/25761602
http://dx.doi.org/10.1136/gutjnl-2014-308323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893119/
https://www.ncbi.nlm.nih.gov/pubmed/25761602
http://dx.doi.org/10.1136/gutjnl-2014-308323

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