Sustained E2F-Dependent Transcription Is a Key Mechanism to Prevent Replication-Stress-Induced DNA Damage

Recent work established DNA replication stress as a crucial driver of genomic instability and a key event at the onset of cancer. Post-translational modifications play an important role in the cellular response to replication stress by regulating the activity of key components to prevent replication...

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Detalles Bibliográficos
Autores principales: Bertoli, Cosetta, Herlihy, Anna E., Pennycook, Betheney R., Kriston-Vizi, Janos, de Bruin, Robertus A.M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893157/
https://www.ncbi.nlm.nih.gov/pubmed/27160911
http://dx.doi.org/10.1016/j.celrep.2016.04.036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893157/
https://www.ncbi.nlm.nih.gov/pubmed/27160911
http://dx.doi.org/10.1016/j.celrep.2016.04.036

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