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Expression of importin-α isoforms in human nasal mucosa: implication for adaptation of avian influenza A viruses to human host

BACKGROUND: Transportation into the host cell nucleus is crucial for replication and transcription of influenza virus. The classical nuclear import is regulated by specific cellular factor, importin-α. Seven isoforms of importin-α have been identified in human. The preference of importin-α3 of avian...

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Detalles Bibliográficos
Autores principales: Ninpan, Khwansiri, Suptawiwat, Ornpreya, Boonarkart, Chompunuch, Phuangphung, Peerayuht, Sathirareuangchai, Sakda, Uiprasertkul, Mongkol, Auewarakul, Prasert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893243/
https://www.ncbi.nlm.nih.gov/pubmed/27260303
http://dx.doi.org/10.1186/s12985-016-0546-y