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AG490 suppresses EPO-mediated activation of JAK2-STAT but enhances blood flow recovery in rats with critical limb ischemia

BACKGROUND: Erythropoietin (EPO) has been demonstrated to enhance recovery in ischemic organs through enhancing angiogenesis. In this study, we used an experimental critical limb ischemia (CLI) rat model to reveal the underlying mechanisms and directly examine the benefits of the anti-apoptotic capa...

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Detalles Bibliográficos
Autores principales:	Chai, Han-Tan, Yip, Hon-Kan, Sun, Cheuk-Kwan, Hsu, Shu-Yuan, Leu, Steve
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893245/ https://www.ncbi.nlm.nih.gov/pubmed/27274711 http://dx.doi.org/10.1186/s12950-016-0126-3

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