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Characterization of genome-reduced Bacillus subtilis strains and their application for the production of guanosine and thymidine
BACKGROUND: Genome streamlining has emerged as an effective strategy to boost the production efficiency of bio-based products. Many efforts have been made to construct desirable chassis cells by reducing the genome size of microbes. It has been reported that the genome-reduced Bacillus subtilis stra...
Autores principales: | Li, Yang, Zhu, Xujun, Zhang, Xueyu, Fu, Jing, Wang, Zhiwen, Chen, Tao, Zhao, Xueming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893254/ https://www.ncbi.nlm.nih.gov/pubmed/27260256 http://dx.doi.org/10.1186/s12934-016-0494-7 |
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