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A live attenuated Salmonella Enteritidis secreting detoxified heat labile toxin enhances mucosal immunity and confers protection against wild-type challenge in chickens

A live attenuated Salmonella Enteritidis (SE) capable of constitutively secreting detoxified double mutant Escherichia coli heat labile toxin (dmLT) was developed. The biologically adjuvanted strain was generated via transformation of a highly immunogenic SE JOL1087 with a plasmid encoding dmLT gene...

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Detalles Bibliográficos
Autores principales:	Lalsiamthara, Jonathan, Kamble, Nitin Machindra, Lee, John Hwa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893257/ https://www.ncbi.nlm.nih.gov/pubmed/27262338 http://dx.doi.org/10.1186/s13567-016-0348-7

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