Histamine induces microglia activation and dopaminergic neuronal toxicity via H1 receptor activation

BACKGROUND: Histamine is an amine widely known as a peripheral inflammatory mediator and as a neurotransmitter in the central nervous system. Recently, it has been suggested that histamine acts as an innate modulator of microglial activity. Herein, we aimed to disclose the role of histamine in micro...

Descripción completa

Detalles Bibliográficos
Autores principales: Rocha, Sandra M., Saraiva, Tatiana, Cristóvão, Ana C., Ferreira, Raquel, Santos, Tiago, Esteves, Marta, Saraiva, Cláudia, Je, Goun, Cortes, Luísa, Valero, Jorge, Alves, Gilberto, Klibanov, Alexander, Kim, Yoon-Seong, Bernardino, Liliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893260/
https://www.ncbi.nlm.nih.gov/pubmed/27260166
http://dx.doi.org/10.1186/s12974-016-0600-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893260/
https://www.ncbi.nlm.nih.gov/pubmed/27260166
http://dx.doi.org/10.1186/s12974-016-0600-0

Ejemplares similares