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Axonal transport of AAV9 in nonhuman primate brain

A pilot study in nonhuman primates (NHP) was conducted in which two Rhesus macaques receive d bilateral parenchymal infusions of adeno-associated virus serotype 9 encoding green fluorescent protein (AAV9-GFP) into each putamen. The post-surgical in-life was restricted to 3 weeks in order to minimize...

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Detalles Bibliográficos
Autores principales: Green, Foad, Samaranch, Lluis, Zhang, H. Steve, Manning-Bog, Amy, Meyer, Kathleen, Forsayeth, John, Bankiewicz, Krystof S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893316/
https://www.ncbi.nlm.nih.gov/pubmed/26953486
http://dx.doi.org/10.1038/gt.2016.24