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Intratracheal myriocin enhances allergen‐induced Th2 inflammation and airway hyper‐responsiveness
INTRODUCTION: Ceramide is the central substrate of sphingolipid metabolism and plays a key role in cellular signal transduction pathways, regulating apoptosis, differentiation, and chemotaxis. Alterations in airway ceramide levels are observed in multiple pulmonary diseases and recent human genetic...
Autores principales: | Edukulla, Ramakrishna, Rehn, Kira Lee, Liu, Bo, McAlees, Jaclyn W., Hershey, Gurjit K., Wang, Yui Hsi, Lewkowich, Ian, Lindsley, Andrew W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893390/ https://www.ncbi.nlm.nih.gov/pubmed/27621809 http://dx.doi.org/10.1002/iid3.110 |
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