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Evaluation of the immunogenicity and protective effects of a trivalent chimeric norovirus P particle immunogen displaying influenza HA2 from subtypes H1, H3 and B

The ectodomain of the influenza A virus (IAV) hemagglutinin (HA) stem is highly conserved across strains and has shown promise as a universal influenza vaccine in a mouse model. In this study, potential B-cell epitopes were found through sequence alignment and epitope prediction in a stem fragment,...

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Detalles Bibliográficos
Autores principales: Gong, Xin, Yin, He, Shi, Yuhua, He, Xiaoqiu, Yu, Yongjiao, Guan, Shanshan, Kuai, Ziyu, Haji, Nasteha M, Haji, Nafisa M, Kong, Wei, Shan, Yaming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893548/
https://www.ncbi.nlm.nih.gov/pubmed/27222326
http://dx.doi.org/10.1038/emi.2016.51

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