A C-terminally truncated mouse Best3 splice variant targets and alters the ion balance in lysosome-endosome hybrids and the endoplasmic reticulum

The Bestrophin family has been characterized as Cl(−) channels in mammals and Na(+) channels in bacteria, but their exact physiological roles remian unknown. In this study, a natural C-terminally truncated variant of mouse Bestrophin 3 (Best3V2) expression in myoblasts and muscles is demonstrated. U...

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Detalles Bibliográficos
Autores principales: Wu, Lichang, Sun, Yu, Ma, Liqiao, Zhu, Jun, Zhang, Baoxia, Pan, Qingjie, Li, Yuyin, Liu, Huanqi, Diao, Aipo, Li, Yinchuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893618/
https://www.ncbi.nlm.nih.gov/pubmed/27265833
http://dx.doi.org/10.1038/srep27332

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