Cargando…

Nanodisc-cell fusion: control of fusion pore nucleation and lifetimes by SNARE protein transmembrane domains

The initial, nanometer-sized connection between the plasma membrane and a hormone- or neurotransmitter-filled vesicle –the fusion pore– can flicker open and closed repeatedly before dilating or resealing irreversibly. Pore dynamics determine release and vesicle recycling kinetics, but pore propertie...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Zhenyong, Auclair, Sarah M., Bello, Oscar, Vennekate, Wensi, Dudzinski, Natasha R., Krishnakumar, Shyam S., Karatekin, Erdem
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893671/
https://www.ncbi.nlm.nih.gov/pubmed/27264104
http://dx.doi.org/10.1038/srep27287

Ejemplares similares