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Nanodisc-cell fusion: control of fusion pore nucleation and lifetimes by SNARE protein transmembrane domains
The initial, nanometer-sized connection between the plasma membrane and a hormone- or neurotransmitter-filled vesicle –the fusion pore– can flicker open and closed repeatedly before dilating or resealing irreversibly. Pore dynamics determine release and vesicle recycling kinetics, but pore propertie...
Autores principales: | Wu, Zhenyong, Auclair, Sarah M., Bello, Oscar, Vennekate, Wensi, Dudzinski, Natasha R., Krishnakumar, Shyam S., Karatekin, Erdem |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893671/ https://www.ncbi.nlm.nih.gov/pubmed/27264104 http://dx.doi.org/10.1038/srep27287 |
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