Germ cell specific overactivation of WNT/βcatenin signalling has no effect on folliculogenesis but causes fertility defects due to abnormal foetal development

All the major components of the WNT signalling pathway are expressed in female germ cells and embryos. However, their functional relevance in oocyte biology is currently unclear. We examined ovaries collected from TCFGFP mice, a well-known Wnt reporter mouse model, and found dynamic changes in the W...

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Detalles Bibliográficos
Autores principales: Kumar, Manish, Camlin, Nicole J., Holt, Janet E., Teixeira, Jose M., McLaughlin, Eileen A., Tanwar, Pradeep S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893675/
https://www.ncbi.nlm.nih.gov/pubmed/27265527
http://dx.doi.org/10.1038/srep27273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893675/
https://www.ncbi.nlm.nih.gov/pubmed/27265527
http://dx.doi.org/10.1038/srep27273

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