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Critical behavior in a stochastic model of vector mediated epidemics

The extreme vulnerability of humans to new and old pathogens is constantly highlighted by unbound outbreaks of epidemics. This vulnerability is both direct, producing illness in humans (dengue, malaria), and also indirect, affecting its supplies (bird and swine flu, Pierce disease, and olive quick d...

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Autores principales: Alfinito, E., Beccaria, M., Macorini, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893676/
https://www.ncbi.nlm.nih.gov/pubmed/27264105
http://dx.doi.org/10.1038/srep27202
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author Alfinito, E.
Beccaria, M.
Macorini, G.
author_facet Alfinito, E.
Beccaria, M.
Macorini, G.
author_sort Alfinito, E.
collection PubMed
description The extreme vulnerability of humans to new and old pathogens is constantly highlighted by unbound outbreaks of epidemics. This vulnerability is both direct, producing illness in humans (dengue, malaria), and also indirect, affecting its supplies (bird and swine flu, Pierce disease, and olive quick decline syndrome). In most cases, the pathogens responsible for an illness spread through vectors. In general, disease evolution may be an uncontrollable propagation or a transient outbreak with limited diffusion. This depends on the physiological parameters of hosts and vectors (susceptibility to the illness, virulence, chronicity of the disease, lifetime of the vectors, etc.). In this perspective and with these motivations, we analyzed a stochastic lattice model able to capture the critical behavior of such epidemics over a limited time horizon and with a finite amount of resources. The model exhibits a critical line of transition that separates spreading and non-spreading phases. The critical line is studied with new analytical methods and direct simulations. Critical exponents are found to be the same as those of dynamical percolation.
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spelling pubmed-48936762016-06-10 Critical behavior in a stochastic model of vector mediated epidemics Alfinito, E. Beccaria, M. Macorini, G. Sci Rep Article The extreme vulnerability of humans to new and old pathogens is constantly highlighted by unbound outbreaks of epidemics. This vulnerability is both direct, producing illness in humans (dengue, malaria), and also indirect, affecting its supplies (bird and swine flu, Pierce disease, and olive quick decline syndrome). In most cases, the pathogens responsible for an illness spread through vectors. In general, disease evolution may be an uncontrollable propagation or a transient outbreak with limited diffusion. This depends on the physiological parameters of hosts and vectors (susceptibility to the illness, virulence, chronicity of the disease, lifetime of the vectors, etc.). In this perspective and with these motivations, we analyzed a stochastic lattice model able to capture the critical behavior of such epidemics over a limited time horizon and with a finite amount of resources. The model exhibits a critical line of transition that separates spreading and non-spreading phases. The critical line is studied with new analytical methods and direct simulations. Critical exponents are found to be the same as those of dynamical percolation. Nature Publishing Group 2016-06-06 /pmc/articles/PMC4893676/ /pubmed/27264105 http://dx.doi.org/10.1038/srep27202 Text en Copyright © 2016, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Alfinito, E.
Beccaria, M.
Macorini, G.
Critical behavior in a stochastic model of vector mediated epidemics
title Critical behavior in a stochastic model of vector mediated epidemics
title_full Critical behavior in a stochastic model of vector mediated epidemics
title_fullStr Critical behavior in a stochastic model of vector mediated epidemics
title_full_unstemmed Critical behavior in a stochastic model of vector mediated epidemics
title_short Critical behavior in a stochastic model of vector mediated epidemics
title_sort critical behavior in a stochastic model of vector mediated epidemics
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893676/
https://www.ncbi.nlm.nih.gov/pubmed/27264105
http://dx.doi.org/10.1038/srep27202
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