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NADPH Oxidase-4 Overexpression Is Associated With Epithelial Ciliary Dysfunction in Neutrophilic Asthma

BACKGROUND: Bronchial epithelial ciliary dysfunction is an important feature of asthma. We sought to determine the role in asthma of neutrophilic inflammation and nicotinamide adenine dinucleotide phosphate (NADPH) oxidases in ciliary dysfunction. METHODS: Bronchial epithelial ciliary function was a...

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Detalles Bibliográficos
Autores principales: Wan, Wing-Yan Heidi, Hollins, Fay, Haste, Louise, Woodman, Lucy, Hirst, Robert A., Bolton, Sarah, Gomez, Edith, Sutcliffe, Amanda, Desai, Dhananjay, Chachi, Latifa, Mistry, Vijay, Szyndralewiez, Cédric, Wardlaw, Andrew, Saunders, Ruth, O’Callaghan, Christopher, Andrew, Peter W., Brightling, Christopher E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Chest Physicians 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893823/
https://www.ncbi.nlm.nih.gov/pubmed/26836936
http://dx.doi.org/10.1016/j.chest.2016.01.024