Protocol of a randomised phase III clinical trial of sequential capecitabine or 5-fluorouracil plus bevacizumab (Cape/5-FU-Bmab) to capecitabine or 5-fluorouracil plus oxaliplatin plus bevacizumab (CapeOX/mFOLFOX6-Bmab) versus combination CapeOX/mFOLFOX6-Bmab in advanced colorectal cancer: the C-cubed (C(3)) study

INTRODUCTION: Results from several randomised trials suggest that the sequential use of cytotoxic agents in patients with metastatic colorectal cancer (mCRC) has the potential to improve overall survival compared with combination chemotherapy. This study is designed to investigate whether sequential...

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Detalles Bibliográficos
Autores principales: Nagasaka, Takeshi, Mishima, Hideyuki, Sawaki, Akira, Shimokawa, Mototsugu, Inukai, Michio, Shinozaki, Katsunori, Tanioka, Hiroaki, Nasu, Junichiro, Nishina, Tomohiro, Hazama, Shoichi, Okajima, Masazumi, Yamaguchi, Yoshiyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2016
Materias:
Gastroenterology and Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893850/
https://www.ncbi.nlm.nih.gov/pubmed/27256093
http://dx.doi.org/10.1136/bmjopen-2016-011454

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