Cargando…

Investigation of salicylate hepatic responses in comparison with chemical analogues of the drug

Anti-hyperglycaemic effects of the hydroxybenzoic acid salicylate might stem from effects of the drug on mitochondrial uncoupling, activation of AMP-activated protein kinase, and inhibition of NF-κB signalling. Here, we have gauged the contribution of these effects to control of hepatocyte glucose p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cameron, Amy R., Logie, Lisa, Patel, Kashyap, Bacon, Sandra, Forteath, Calum, Harthill, Jean, Roberts, Adam, Sutherland, Calum, Stewart, Derek, Viollet, Benoit, Sakamoto, Kei, McDougall, Gordon, Foretz, Marc, Rena, Graham
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier Pub. Co 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894248/ https://www.ncbi.nlm.nih.gov/pubmed/27130437 http://dx.doi.org/10.1016/j.bbadis.2016.04.015

Ejemplares similares

Metformin selectively targets redox control of complex I energy transduction
por: Cameron, Amy R., et al.
Publicado: (2017)

Cellular Responses to the Metal-Binding Properties of Metformin
por: Logie, Lisa, et al.
Publicado: (2012)

Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status
por: Cameron, Amy R., et al.
Publicado: (2016)

Amino acid homeostasis is a target of metformin therapy
por: Forteath, Calum, et al.
Publicado: (2023)

Salicylic acid: old and new implications for the treatment of type 2 diabetes?
por: Rena, Graham, et al.
Publicado: (2014)

Regulation of hepatic glucose production and AMPK by AICAR but not by metformin depends on drug uptake through the equilibrative nucleoside transporter 1 (ENT1)
por: Logie, Lisa, et al.
Publicado: (2018)

The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver
por: Patel, Kashyap, et al.
Publicado: (2014)

Activation of AMPK for a Break in Hepatic Lipid Accumulation and Circulating Cholesterol
por: Foretz, Marc, et al.
Publicado: (2018)

Metformin: update on mechanisms of action and repurposing potential
por: Foretz, Marc, et al.
Publicado: (2023)

AMPK Activation Reduces Hepatic Lipid Content by Increasing Fat Oxidation In Vivo
por: Foretz, Marc, et al.
Publicado: (2018)

AMPK is not required for the effect of metformin on the inhibition of BMP6-induced hepcidin gene expression in hepatocytes
por: Deschemin, Jean-Christophe, et al.
Publicado: (2017)

Editorial: Metformin: Beyond Diabetes
por: Bost, Frédéric, et al.
Publicado: (2019)

AMPK integrates metabolite and kinase-based immunometabolic control in macrophages
por: Phair, Iain R., et al.
Publicado: (2022)

What Are the bona fide GSK3 Substrates?
por: Sutherland, Calum
Publicado: (2011)

Adenosine-Mono-Phosphate-Activated Protein Kinase-Independent Effects of Metformin in T Cells
por: Zarrouk, Marouan, et al.
Publicado: (2014)

Obesity Impairs Skeletal Muscle Regeneration Through Inhibition of AMPK
por: Fu, Xing, et al.
Publicado: (2016)

AMPK Re-Activation Suppresses Hepatic Steatosis but its Downregulation Does Not Promote Fatty Liver Development
por: Boudaba, Nadia, et al.
Publicado: (2018)

AMPK Activation Promotes Tight Junction Assembly in Intestinal Epithelial Caco-2 Cells
por: Olivier, Séverine, et al.
Publicado: (2019)

AMPK promotes induction of the tumor suppressor FLCN through activation of TFEB independently of mTOR
por: Collodet, Caterina, et al.
Publicado: (2019)

Increased FAT/CD36 Cycling and Lipid Accumulation in Myotubes Derived from Obese Type 2 Diabetic Patients
por: Aguer, Celine, et al.
Publicado: (2011)

Biguanides suppress hepatic glucagon signaling by decreasing production of cyclic AMP
por: Miller, Russell A., et al.
Publicado: (2013)

AMPKα1: A glucose sensor that controls CD8 T-cell memory
por: Rolf, Julia, et al.
Publicado: (2013)

Hypoglycemia-Sensing Neurons of the Ventromedial Hypothalamus Require AMPK-Induced Txn2 Expression but Are Dispensable for Physiological Counterregulation
por: Quenneville, Simon, et al.
Publicado: (2020)

Methyl salicylate 2-O-β-D-lactoside, a novel salicylic acid analogue, acts as an anti-inflammatory agent on microglia and astrocytes
por: Lan, Xi, et al.
Publicado: (2011)

Review: Micronutrient Selenium Deficiency Influences Evolution of Some Viral Infectious Diseases
por: Harthill, Michalann
Publicado: (2011)

Optical analogues of the Newton–Schrödinger equation and boson star evolution
por: Roger, Thomas, et al.
Publicado: (2016)

On Salicylate of Quinine as an Antipyretic
por: Brown, J. Graham
Publicado: (1876)

Salicin, Salicylic Acid and the Salicylates
Publicado: (1878)

Fish–parasite interaction networks reveal latitudinal and taxonomic trends in the structure of host–parasite associations
por: Poulin, Robert, et al.
Publicado: (2022)

AMPK Signaling Involvement for the Repression of the IL-1β-Induced Group IIA Secretory Phospholipase A2 Expression in VSMCs
por: El Hadri, Khadija, et al.
Publicado: (2015)

Specific Deletion of AMP-Activated Protein Kinase (α1AMPK) in Murine Oocytes Alters Junctional Protein Expression and Mitochondrial Physiology
por: Bertoldo, Michael J., et al.
Publicado: (2015)

Elraglusib (formerly 9-ING-41) possesses potent anti-lymphoma properties which cannot be attributed to GSK3 inhibition
por: Coats, Josh T., et al.
Publicado: (2023)

Point-of-care testing of HbA1c levels in community settings for people with established diabetes or people at risk of developing type 2 diabetes: a systematic review and meta-analysis protocol
por: Gourlay, Anna, et al.
Publicado: (2023)

The In Silico Characterization of a Salicylic Acid Analogue Coding Gene Clusters in Selected Pseudomonas fluorescens Strains
por: Shehroz, Muhammad, et al.
Publicado: (2019)

Bi-aryl Analogues of Salicylic Acids: Design, Synthesis and SAR Study to Ameliorate Endoplasmic Reticulum Stress
por: Kim, Ye Eun, et al.
Publicado: (2021)

Anaesthesia generates neuronal insulin resistance by inducing hypothermia
por: Holscher, Christian, et al.
Publicado: (2008)

A partnership with the proteasome; the destructive nature of GSK3
por: Robertson, Holly, et al.
Publicado: (2018)

Bioaccessible Raspberry Extracts Enriched in Ellagitannins and Ellagic Acid Derivatives Have Anti-Neuroinflammatory Properties
por: Garcia, Gonçalo, et al.
Publicado: (2020)

Mitogen and Stress-Activated Kinases 1 and 2 Mediate Endothelial Dysfunction
por: Akbar, Naveed, et al.
Publicado: (2021)

Salicylates
Publicado: (1890)

Cannot write session to /tmp/vufind_sessions/sess_ij17e3vsoi553mhiijd5td16e4