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High-throughput identification and dendritic cell-based functional validation of MHC class I-restricted Mycobacterium tuberculosis epitopes

Emergence of drug-resistant strains of the pathogen Mycobacterium tuberculosis (Mtb) and the ineffectiveness of BCG in curtailing Mtb infection makes vaccine development for tuberculosis an important objective. Identifying immunogenic CD8+ T cell peptide epitopes is necessary for peptide-based vacci...

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Detalles Bibliográficos
Autores principales:	Nair, Smita K., Tomaras, Georgia D., Sales, Ana Paula, Boczkowski, David, Chan, Cliburn, Plonk, Kelly, Cai, Yongting, Dannull, Jens, Kepler, Thomas B., Pruitt, Scott K., Weinhold, Kent J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894389/ https://www.ncbi.nlm.nih.gov/pubmed/24755960 http://dx.doi.org/10.1038/srep04632

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