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Crystal structure of Gib2, a signal-transducing protein scaffold associated with ribosomes in Cryptococcus neoformans
The atypical Gβ-like/RACK1 Gib2 protein promotes cAMP signalling that plays a central role in regulating the virulence of Cryptococcus neoformans. Gib2 contains a seven-bladed β transducin structure and is emerging as a scaffold protein interconnecting signalling pathways through interactions with v...
Autores principales: | Ero, Rya, Dimitrova, Valya Tenusheva, Chen, Yun, Bu, Wenting, Feng, Shu, Liu, Tongbao, Wang, Ping, Xue, Chaoyang, Tan, Suet Mien, Gao, Yong-Gui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894404/ https://www.ncbi.nlm.nih.gov/pubmed/25732347 http://dx.doi.org/10.1038/srep08688 |
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