Macroscopic and Macromolecular Specificity of Alkylphenol Anesthetics for Neuronal Substrates

We used a photoactive general anesthetic called meta-azi-propofol (AziPm) to test the selectivity and specificity of alkylphenol anesthetic binding in mammalian brain. Photolabeling of rat brain sections with [(3)H]AziPm revealed widespread but heterogeneous ligand distribution, with [(3)H]AziPm pre...

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Detalles Bibliográficos
Autores principales: Weiser, Brian P., Hall, Michael A., Weinbren, Nathan L., Woll, Kellie A., Dailey, William P., Eckenhoff, Maryellen F., Eckenhoff, Roderic G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894431/
https://www.ncbi.nlm.nih.gov/pubmed/25853337
http://dx.doi.org/10.1038/srep09695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894431/
https://www.ncbi.nlm.nih.gov/pubmed/25853337
http://dx.doi.org/10.1038/srep09695

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