Cargando…

Gambogic acid induces apoptosis in diffuse large B-cell lymphoma cells via inducing proteasome inhibition

Resistance to chemotherapy is a great challenge to improving the survival of patients with diffuse large B-cell lymphoma (DLBCL), especially those with activated B-cell-like DLBCL (ABC-DLBCL). Therefore it is urgent to search for novel agents for the treatment of DLBCL. Gambogic acid (GA), a small m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Shi, Xianping, Lan, Xiaoying, Chen, Xin, Zhao, Chong, Li, Xiaofen, Liu, Shouting, Huang, Hongbiao, Liu, Ningning, Zang, Dan, Liao, Yuning, Zhang, Peiquan, Wang, Xuejun, Liu, Jinbao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894437/ https://www.ncbi.nlm.nih.gov/pubmed/25853502 http://dx.doi.org/10.1038/srep09694

Ejemplares similares

Repurposing an antidandruff agent to treating cancer: zinc pyrithione inhibits tumor growth via targeting proteasome-associated deubiquitinases
por: Zhao, Chong, et al.
Publicado: (2017)

A novel proteasome inhibitor suppresses tumor growth via targeting both 19S proteasome deubiquitinases and 20S proteolytic peptidases
por: Liu, Ningning, et al.
Publicado: (2014)

Anti-rheumatic agent auranofin induced apoptosis in chronic myeloid leukemia cells resistant to imatinib through both Bcr/Abl-dependent and -independent mechanisms
por: Chen, Xin, et al.
Publicado: (2014)

A microRNA-mediated decrease in eukaryotic initiation factor 2α promotes cell survival during PS-341 treatment
por: Jiang, Lili, et al.
Publicado: (2016)

Bilirubin neurotoxicity is associated with proteasome inhibition
por: Huang, Hongbiao, et al.
Publicado: (2017)

Platinum-containing compound platinum pyrithione is stronger and safer than cisplatin in cancer therapy
por: Zhao, Chong, et al.
Publicado: (2016)

Clinically used antirheumatic agent auranofin is a proteasomal deubiquitinase inhibitor and inhibits tumor growth
por: Liu, Ningning, et al.
Publicado: (2014)

Platinum pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via DUB inhibition-dependent caspase activation and Bcr-Abl downregulation
por: Lan, Xiaoying, et al.
Publicado: (2017)

Proteasomal cysteine deubiquitinase inhibitor b-AP15 suppresses migration and induces apoptosis in diffuse large B cell lymphoma
por: Jiang, Liling, et al.
Publicado: (2019)

Nickel pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via both Bcr/Abl-dependent and Bcr/Abl-independent mechanisms
por: Lan, Xiaoying, et al.
Publicado: (2016)

Proteasome-associated deubiquitinase ubiquitin-specific protease 14 regulates prostate cancer proliferation by deubiquitinating and stabilizing androgen receptor
por: Liao, Yuning, et al.
Publicado: (2017)

Two clinical drugs deubiquitinase inhibitor auranofin and aldehyde dehydrogenase inhibitor disulfiram trigger synergistic anti-tumor effects in vitro and in vivo
por: Huang, Hongbiao, et al.
Publicado: (2015)

Intracellular ATP Concentration Contributes to the Cytotoxic and Cytoprotective Effects of Adenosine
por: Li, Shujue, et al.
Publicado: (2013)

Inhibition of 19S proteasome-associated deubiquitinases by metal-containing compounds
por: Liu, Ningning, et al.
Publicado: (2015)

HDAC Inhibitor L-Carnitine and Proteasome Inhibitor Bortezomib Synergistically Exert Anti-Tumor Activity In Vitro and In Vivo
por: Huang, Hongbiao, et al.
Publicado: (2012)

Targeting proteasome-associated deubiquitinases as a novel strategy for the treatment of estrogen receptor-positive breast cancer
por: Xia, Xiaohong, et al.
Publicado: (2018)

L-Carnitine Is an Endogenous HDAC Inhibitor Selectively Inhibiting Cancer Cell Growth In Vivo and In Vitro
por: Huang, Hongbiao, et al.
Publicado: (2012)

Cytoplasmic RAP1 mediates cisplatin resistance of non-small cell lung cancer
por: Xiao, Lu, et al.
Publicado: (2017)

Cyclin-dependent kinase 7/9 inhibitor SNS-032 induces apoptosis in diffuse large B-cell lymphoma cells
por: Jiang, Liling, et al.
Publicado: (2022)

Autophagy Induced by Proteasomal DUB Inhibitor NiPT Restricts NiPT-Mediated Cancer Cell Death
por: Chen, Jinghong, et al.
Publicado: (2020)

Platinum-containing compound platinum pyrithione suppresses ovarian tumor proliferation through proteasome inhibition
por: Huang, Hongbiao, et al.
Publicado: (2017)

Gambogic Acid Induces Apoptosis of Non-Small Cell Lung Cancer (NSCLC) Cells by Suppressing Notch Signaling
por: Zhu, Minghua, et al.
Publicado: (2018)

A Gamboge Case
por: Biegler, J. A.
Publicado: (1887)

Gambogic acid inhibits growth, induces apoptosis, and overcomes drug resistance in human colorectal cancer cells
por: WEN, CHUANGYU, et al.
Publicado: (2015)

A SIX1 degradation inducer blocks excessive proliferation of prostate cancer
por: Liao, Yuning, et al.
Publicado: (2022)

Hepatic Deficiency of COP9 Signalosome Subunit 8 Induces Ubiquitin-Proteasome System Impairment and Bim-Mediated Apoptosis in Murine Livers
por: Lei, Daoxiong, et al.
Publicado: (2013)

Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination
por: Liao, Yuning, et al.
Publicado: (2018)

Inhibition of EGFR signaling with Spautin-1 represents a novel therapeutics for prostate cancer
por: Liao, Yuning, et al.
Publicado: (2019)

Gambogic acid inhibits thioredoxin activity and induces ROS-mediated cell death in castration-resistant prostate cancer
por: Pan, Hong, et al.
Publicado: (2017)

Nanoscale Features of Gambogic Acid Induced ROS-Dependent Apoptosis in Esophageal Cancer Cells Imaged by Atomic Force Microscopy
por: Liu, Jianxin, et al.
Publicado: (2022)

USP10 modulates the SKP2/Bcr-Abl axis via stabilizing SKP2 in chronic myeloid leukemia
por: Liao, Yuning, et al.
Publicado: (2019)

Gambogic acid suppresses colon cancer cell activity in vitro
por: Zhou, Zailong, et al.
Publicado: (2019)

A new gold(I) complex-Au(PPh(3))PT is a deubiquitinase inhibitor and inhibits tumor growth
por: Li, Xiaofen, et al.
Publicado: (2018)

A novel deubiquitinase inhibitor b-AP15 triggers apoptosis in both androgen receptor-dependent and -independent prostate cancers
por: Cai, Jianyu, et al.
Publicado: (2017)

Inhibition of USP14 enhances the sensitivity of breast cancer to enzalutamide
por: Xia, Xiaohong, et al.
Publicado: (2019)

Cell penetrating peptides functionalized gambogic acid-nanostructured lipid carrier for cancer treatment
por: Huang, Rui, et al.
Publicado: (2018)

Synergistic anti-proliferative effects of gambogic acid with docetaxel in gastrointestinal cancer cell lines
por: Zou, Zhengyun, et al.
Publicado: (2012)

Gambogic Acid as a Candidate for Cancer Therapy: A Review
por: Liu, Yuling, et al.
Publicado: (2020)

Gambogic Acid Lysinate Induces Apoptosis in Breast Cancer MCF-7 Cells by Increasing Reactive Oxygen Species
por: Zhen, Yong-Zhan, et al.
Publicado: (2015)

Gambogic Acid and Piperine Synergistically Induce Apoptosis in Human Cholangiocarcinoma Cell via Caspase and Mitochondria-Mediated Pathway
por: Yapasert, Rittibet, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_3gb4m6jel64nis81h3nmj40g06