Chemical Modulation of the Biological Activity of Reutericyclin: a Membrane-Active Antibiotic from Lactobacillus reuteri

Whilst the development of membrane-active antibiotics is now an attractive therapeutic concept, progress in this area is disadvantaged by poor knowledge of the structure-activity relationship (SAR) required for optimizing molecules to selectively target bacteria. This prompted us to explore the SAR...

Descripción completa

Detalles Bibliográficos
Autores principales: Cherian, Philip T., Wu, Xiaoqian, Maddox, Marcus M., Singh, Aman P., Lee, Richard E., Hurdle, Julian G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894453/
https://www.ncbi.nlm.nih.gov/pubmed/24739957
http://dx.doi.org/10.1038/srep04721

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894453/
https://www.ncbi.nlm.nih.gov/pubmed/24739957
http://dx.doi.org/10.1038/srep04721

Ejemplares similares