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Chemical Modulation of the Biological Activity of Reutericyclin: a Membrane-Active Antibiotic from Lactobacillus reuteri

Whilst the development of membrane-active antibiotics is now an attractive therapeutic concept, progress in this area is disadvantaged by poor knowledge of the structure-activity relationship (SAR) required for optimizing molecules to selectively target bacteria. This prompted us to explore the SAR...

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Detalles Bibliográficos
Autores principales:	Cherian, Philip T., Wu, Xiaoqian, Maddox, Marcus M., Singh, Aman P., Lee, Richard E., Hurdle, Julian G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894453/ https://www.ncbi.nlm.nih.gov/pubmed/24739957 http://dx.doi.org/10.1038/srep04721

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