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Dnmt2/Trdmt1 as Mediator of RNA Polymerase II Transcriptional Activity in Cardiac Growth

Dnmt2/Trdmt1 is a methyltransferase, which has been shown to methylate tRNAs. Deficient mutants were reported to exhibit various, seemingly unrelated, defects in development and RNA-mediated epigenetic heredity. Here we report a role in a distinct developmental regulation effected by a noncoding RNA...

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Detalles Bibliográficos
Autores principales: Ghanbarian, Hossein, Wagner, Nicole, Polo, Beatrice, Baudouy, Delphine, Kiani, Jafar, Michiels, Jean-François, Cuzin, François, Rassoulzadegan, Minoo, Wagner, Kay-Dietrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894585/
https://www.ncbi.nlm.nih.gov/pubmed/27270731
http://dx.doi.org/10.1371/journal.pone.0156953