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Impact on Life Expectancy of Withdrawing Thiopurines in Patients with Crohn’s Disease in Sustained Clinical Remission: A Lifetime Risk-Benefit Analysis

OBJECTIVE: Long-term treatment with thiopurines is associated with a decreased risk of Crohn’s disease (CD) flare but an increased risk of various cancers depending on gender, age, and presence of extensive colitis. We evaluated risks and benefits of withdrawing thiopurines in patients with CD in pr...

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Detalles Bibliográficos
Autores principales:	Kirchgesner, Julien, Beaugerie, Laurent, Carrat, Fabrice, Sokol, Harry, Cosnes, Jacques, Schwarzinger, Michaël
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894633/ https://www.ncbi.nlm.nih.gov/pubmed/27271176 http://dx.doi.org/10.1371/journal.pone.0157191

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