Relative Contributions of Prenylation and Postprenylation Processing in Cryptococcus neoformans Pathogenesis

Prenyltransferase enzymes promote the membrane localization of their target proteins by directing the attachment of a hydrophobic lipid group at a conserved C-terminal CAAX motif. Subsequently, the prenylated protein is further modified by postprenylation processing enzymes that cleave the terminal...

Descripción completa

Detalles Bibliográficos
Autores principales: Esher, Shannon K., Ost, Kyla S., Kozubowski, Lukasz, Yang, Dong-Hoon, Kim, Min Su, Bahn, Yong-Sun, Alspaugh, J. Andrew, Nichols, Connie B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894686/
https://www.ncbi.nlm.nih.gov/pubmed/27303728
http://dx.doi.org/10.1128/mSphere.00084-15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894686/
https://www.ncbi.nlm.nih.gov/pubmed/27303728
http://dx.doi.org/10.1128/mSphere.00084-15

Ejemplares similares