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Relative Contributions of Prenylation and Postprenylation Processing in Cryptococcus neoformans Pathogenesis

Prenyltransferase enzymes promote the membrane localization of their target proteins by directing the attachment of a hydrophobic lipid group at a conserved C-terminal CAAX motif. Subsequently, the prenylated protein is further modified by postprenylation processing enzymes that cleave the terminal...

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Detalles Bibliográficos
Autores principales:	Esher, Shannon K., Ost, Kyla S., Kozubowski, Lukasz, Yang, Dong-Hoon, Kim, Min Su, Bahn, Yong-Sun, Alspaugh, J. Andrew, Nichols, Connie B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894686/ https://www.ncbi.nlm.nih.gov/pubmed/27303728 http://dx.doi.org/10.1128/mSphere.00084-15

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