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Mouse Adenovirus Type 1 Early Region 1A Effects on the Blood-Brain Barrier

Mouse adenovirus type 1 (MAV-1) infects endothelial cells and disrupts the blood-brain barrier (BBB), causing encephalitis in inbred and outbred mice. Using a virus mutant that does not produce the early region 1A protein E1A, we investigated whether the activity of this known viral transcriptional...

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Detalles Bibliográficos
Autores principales: Tirumuru, Nagaraja, Pretto, Carla D., Castro Jorge, Luiza A., Spindler, Katherine R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894691/
https://www.ncbi.nlm.nih.gov/pubmed/27303733
http://dx.doi.org/10.1128/mSphere.00079-16