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Idiopathic Hypereosinophilic Syndrome With Cutaneous Manifestations and Flame Figures: A Spectrum of Eosinophilic Dermatoses Whose Features Overlap With Wells' Syndrome
IMPORTANCE: Wells syndrome (WS) (eosinophilic cellulitis) is an uncommon eosinophilic dermatitis that has been rarely described in association with, but distinct from, hypereosinophilic syndrome (HES). OBSERVATIONS: We report a case of an eosinophilic dermatosis with flame figures in association wit...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Journal of Dermatopathology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894797/ https://www.ncbi.nlm.nih.gov/pubmed/25839890 http://dx.doi.org/10.1097/DAD.0000000000000279 |
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author | Smith, Sabrina M. Kiracofe, Elizabeth A. Clark, Lindsey N. Gru, Alejandro A. |
author_facet | Smith, Sabrina M. Kiracofe, Elizabeth A. Clark, Lindsey N. Gru, Alejandro A. |
author_sort | Smith, Sabrina M. |
collection | PubMed |
description | IMPORTANCE: Wells syndrome (WS) (eosinophilic cellulitis) is an uncommon eosinophilic dermatitis that has been rarely described in association with, but distinct from, hypereosinophilic syndrome (HES). OBSERVATIONS: We report a case of an eosinophilic dermatosis with flame figures in association with idiopathic HES, manifested by inflammatory myocarditis, asthma, and peripheral blood eosinophilia. CONCLUSIONS AND RELEVANCE: The diagnoses of WS and HES, rather than being distinct findings, may represent 2 entities on a spectrum of hypereosinophilic diseases. The diagnosis of WS should be made with caution and should prompt a thorough investigation that includes a work-up for a systemic eosinophilic disorder. |
format | Online Article Text |
id | pubmed-4894797 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | The American Journal of Dermatopathology |
record_format | MEDLINE/PubMed |
spelling | pubmed-48947972016-06-21 Idiopathic Hypereosinophilic Syndrome With Cutaneous Manifestations and Flame Figures: A Spectrum of Eosinophilic Dermatoses Whose Features Overlap With Wells' Syndrome Smith, Sabrina M. Kiracofe, Elizabeth A. Clark, Lindsey N. Gru, Alejandro A. Am J Dermatopathol Extraordinary Case Report IMPORTANCE: Wells syndrome (WS) (eosinophilic cellulitis) is an uncommon eosinophilic dermatitis that has been rarely described in association with, but distinct from, hypereosinophilic syndrome (HES). OBSERVATIONS: We report a case of an eosinophilic dermatosis with flame figures in association with idiopathic HES, manifested by inflammatory myocarditis, asthma, and peripheral blood eosinophilia. CONCLUSIONS AND RELEVANCE: The diagnoses of WS and HES, rather than being distinct findings, may represent 2 entities on a spectrum of hypereosinophilic diseases. The diagnosis of WS should be made with caution and should prompt a thorough investigation that includes a work-up for a systemic eosinophilic disorder. The American Journal of Dermatopathology 2015-12 2015-11-20 /pmc/articles/PMC4894797/ /pubmed/25839890 http://dx.doi.org/10.1097/DAD.0000000000000279 Text en Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved. |
spellingShingle | Extraordinary Case Report Smith, Sabrina M. Kiracofe, Elizabeth A. Clark, Lindsey N. Gru, Alejandro A. Idiopathic Hypereosinophilic Syndrome With Cutaneous Manifestations and Flame Figures: A Spectrum of Eosinophilic Dermatoses Whose Features Overlap With Wells' Syndrome |
title | Idiopathic Hypereosinophilic Syndrome With Cutaneous Manifestations and Flame Figures: A Spectrum of Eosinophilic Dermatoses Whose Features Overlap With Wells' Syndrome |
title_full | Idiopathic Hypereosinophilic Syndrome With Cutaneous Manifestations and Flame Figures: A Spectrum of Eosinophilic Dermatoses Whose Features Overlap With Wells' Syndrome |
title_fullStr | Idiopathic Hypereosinophilic Syndrome With Cutaneous Manifestations and Flame Figures: A Spectrum of Eosinophilic Dermatoses Whose Features Overlap With Wells' Syndrome |
title_full_unstemmed | Idiopathic Hypereosinophilic Syndrome With Cutaneous Manifestations and Flame Figures: A Spectrum of Eosinophilic Dermatoses Whose Features Overlap With Wells' Syndrome |
title_short | Idiopathic Hypereosinophilic Syndrome With Cutaneous Manifestations and Flame Figures: A Spectrum of Eosinophilic Dermatoses Whose Features Overlap With Wells' Syndrome |
title_sort | idiopathic hypereosinophilic syndrome with cutaneous manifestations and flame figures: a spectrum of eosinophilic dermatoses whose features overlap with wells' syndrome |
topic | Extraordinary Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894797/ https://www.ncbi.nlm.nih.gov/pubmed/25839890 http://dx.doi.org/10.1097/DAD.0000000000000279 |
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