MAP Kinase Pathways: Molecular Roads to Primary Acral Lentiginous Melanoma

The etiology and pathogenesis of lentiginous acral melanomas are poorly understood. Recent studies have postulated that DNA repair mechanisms and cell growth pathways are involved in the development of melanoma, particularly changes in the MAPK pathways (RAS, BRAF, MEK 1/2, and ERK 1/2). The aim of...

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Detalles Bibliográficos
Autores principales: Fernandes, Juliana D., Hsieh, Ricardo, de Freitas, Luiz A. R., Brandao, Miguel A. R., Lourenço, Silvia V., Sangueza, Martin, Nico, Marcello M. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Journal of Dermatopathology 2015
Materias:
Original Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894812/
https://www.ncbi.nlm.nih.gov/pubmed/26588333
http://dx.doi.org/10.1097/DAD.0000000000000317

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