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The function of the two-pore channel TPC1 depends on dimerization of its carboxy-terminal helix

Two-pore channels (TPCs) constitute a family of intracellular cation channels with diverse permeation properties and functions in animals and plants. In the model plant Arabidopsis, the vacuolar cation channel TPC1 is involved in propagation of calcium waves and in cation homeostasis. Here, we disco...

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Detalles Bibliográficos
Autores principales: Larisch, Nina, Kirsch, Sonja A., Schambony, Alexandra, Studtrucker, Tanja, Böckmann, Rainer A., Dietrich, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894940/
https://www.ncbi.nlm.nih.gov/pubmed/26781468
http://dx.doi.org/10.1007/s00018-016-2131-3