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Mining 3D genome structure populations identifies major factors governing the stability of regulatory communities
Three-dimensional (3D) genome structures vary from cell to cell even in an isogenic sample. Unlike protein structures, genome structures are highly plastic, posing a significant challenge for structure-function mapping. Here we report an approach to comprehensively identify 3D chromatin clusters tha...
Autores principales: | Dai, Chao, Li, Wenyuan, Tjong, Harianto, Hao, Shengli, Zhou, Yonggang, Li, Qingjiao, Chen, Lin, Zhu, Bing, Alber, Frank, Jasmine Zhou, Xianghong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895025/ https://www.ncbi.nlm.nih.gov/pubmed/27240697 http://dx.doi.org/10.1038/ncomms11549 |
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