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miRNA-375 a Sensor of Glucotoxicity Is Altered in the Serum of Children with Newly Diagnosed Type 1 Diabetes

Background. The use of miRNAs as biomarkers for Type 1 Diabetes (T1D) risk is attractive as T1D is usually diagnosed in front of acute symptoms. As miR-375 is highly expressed in the endocrine pancreas, we postulated that its circulating level might reflect beta cell alterations and might be altered...

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Detalles Bibliográficos
Autores principales: Marchand, Lucien, Jalabert, Audrey, Meugnier, Emmanuelle, Van den Hende, Kathleen, Fabien, Nicole, Nicolino, Marc, Madec, Anne-Marie, Thivolet, Charles, Rome, Sophie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895032/
https://www.ncbi.nlm.nih.gov/pubmed/27314045
http://dx.doi.org/10.1155/2016/1869082