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CXCL1 mediates obesity-associated adipose stromal cell trafficking and function in the tumour microenvironment
White adipose tissue (WAT) overgrowth in obesity is linked with increased aggressiveness of certain cancers. Adipose stromal cells (ASCs) can become mobilized from WAT, recruited by tumours and promote cancer progression. Mechanisms underlying ASC trafficking are unclear. Here we demonstrate that ch...
Autores principales: | Zhang, Tao, Tseng, Chieh, Zhang, Yan, Sirin, Olga, Corn, Paul G., Li-Ning-Tapia, Elsa M., Troncoso, Patricia, Davis, John, Pettaway, Curtis, Ward, John, Frazier, Marsha L., Logothetis, Christopher, Kolonin, Mikhail G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895055/ https://www.ncbi.nlm.nih.gov/pubmed/27241286 http://dx.doi.org/10.1038/ncomms11674 |
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