Retinopathy and Uveitis Associated with Sofosbuvir Therapy for Chronic Hepatitis C Infection

Purpose: We report a case of retinopathy and uveitis associated with sofosbuvir therapy for hepatitis C infection. Methods: Case report. Results: A 57-year-old-male developed ocular inflammation and retinopathy four weeks after the administration of sofosbuvir for a hepatitis C infection. Hearing lo...

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Autores principales: Chin-Loy, Katrina, Galaydh, Farah, Shaikh, Saad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2016
Materias:
Ophthalmology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895080/
https://www.ncbi.nlm.nih.gov/pubmed/27335709
http://dx.doi.org/10.7759/cureus.597
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author Chin-Loy, Katrina
Galaydh, Farah
Shaikh, Saad
author_facet Chin-Loy, Katrina
Galaydh, Farah
Shaikh, Saad
author_sort Chin-Loy, Katrina
collection PubMed
description Purpose: We report a case of retinopathy and uveitis associated with sofosbuvir therapy for hepatitis C infection. Methods: Case report. Results: A 57-year-old-male developed ocular inflammation and retinopathy four weeks after the administration of sofosbuvir for a hepatitis C infection. Hearing loss, rheumatologic disease, and essential tremor were also noted. The ophthalmic findings resolved with discontinuation of the drug.    Conclusion:  The authors report a case of sofosbuvir induced retinopathy and uveitis, the first associated with this emerging therapy for hepatitis C. Ophthalmologists and other treating physicians should be aware of the ophthalmic side effects of this drug. 
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spelling pubmed-48950802016-06-22 Retinopathy and Uveitis Associated with Sofosbuvir Therapy for Chronic Hepatitis C Infection Chin-Loy, Katrina Galaydh, Farah Shaikh, Saad Cureus Ophthalmology Purpose: We report a case of retinopathy and uveitis associated with sofosbuvir therapy for hepatitis C infection. Methods: Case report. Results: A 57-year-old-male developed ocular inflammation and retinopathy four weeks after the administration of sofosbuvir for a hepatitis C infection. Hearing loss, rheumatologic disease, and essential tremor were also noted. The ophthalmic findings resolved with discontinuation of the drug.    Conclusion:  The authors report a case of sofosbuvir induced retinopathy and uveitis, the first associated with this emerging therapy for hepatitis C. Ophthalmologists and other treating physicians should be aware of the ophthalmic side effects of this drug.  Cureus 2016-05-03 /pmc/articles/PMC4895080/ /pubmed/27335709 http://dx.doi.org/10.7759/cureus.597 Text en Copyright © 2016, Chin-Loy et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Ophthalmology
Chin-Loy, Katrina
Galaydh, Farah
Shaikh, Saad
Retinopathy and Uveitis Associated with Sofosbuvir Therapy for Chronic Hepatitis C Infection
title Retinopathy and Uveitis Associated with Sofosbuvir Therapy for Chronic Hepatitis C Infection
title_full Retinopathy and Uveitis Associated with Sofosbuvir Therapy for Chronic Hepatitis C Infection
title_fullStr Retinopathy and Uveitis Associated with Sofosbuvir Therapy for Chronic Hepatitis C Infection
title_full_unstemmed Retinopathy and Uveitis Associated with Sofosbuvir Therapy for Chronic Hepatitis C Infection
title_short Retinopathy and Uveitis Associated with Sofosbuvir Therapy for Chronic Hepatitis C Infection
title_sort retinopathy and uveitis associated with sofosbuvir therapy for chronic hepatitis c infection
topic Ophthalmology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895080/
https://www.ncbi.nlm.nih.gov/pubmed/27335709
http://dx.doi.org/10.7759/cureus.597
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AT galaydhfarah retinopathyanduveitisassociatedwithsofosbuvirtherapyforchronichepatitiscinfection
AT shaikhsaad retinopathyanduveitisassociatedwithsofosbuvirtherapyforchronichepatitiscinfection

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