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Predicting transcription factor site occupancy using DNA sequence intrinsic and cell-type specific chromatin features
BACKGROUND: Understanding the mechanisms by which transcription factors (TF) are recruited to their physiological target sites is crucial for understanding gene regulation. DNA sequence intrinsic features such as predicted binding affinity are often not very effective in predicting in vivo site occu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895346/ https://www.ncbi.nlm.nih.gov/pubmed/26818008 http://dx.doi.org/10.1186/s12859-015-0846-z |