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Effect of a p38 MAPK inhibitor on FFA-induced hepatic insulin resistance in vivo

The mechanisms whereby prolonged plasma free fatty acids elevation, as found in obesity, causes hepatic insulin resistance are not fully clarified. We herein investigated whether inhibition of p38 mitogen-activated protein kinase (MAPK) prevented hepatic insulin resistance following prolonged lipid...

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Detalles Bibliográficos
Autores principales: Pereira, S, Yu, W Q, Moore, J, Mori, Y, Tsiani, E, Giacca, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895375/
https://www.ncbi.nlm.nih.gov/pubmed/27136448
http://dx.doi.org/10.1038/nutd.2016.11