Cargando…
Effect of a p38 MAPK inhibitor on FFA-induced hepatic insulin resistance in vivo
The mechanisms whereby prolonged plasma free fatty acids elevation, as found in obesity, causes hepatic insulin resistance are not fully clarified. We herein investigated whether inhibition of p38 mitogen-activated protein kinase (MAPK) prevented hepatic insulin resistance following prolonged lipid...
Autores principales: | Pereira, S, Yu, W Q, Moore, J, Mori, Y, Tsiani, E, Giacca, A |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895375/ https://www.ncbi.nlm.nih.gov/pubmed/27136448 http://dx.doi.org/10.1038/nutd.2016.11 |
Ejemplares similares
-
Attenuation of Free Fatty Acid (FFA)-Induced Skeletal Muscle Cell Insulin Resistance by Resveratrol is Linked to Activation of AMPK and Inhibition of mTOR and p70 S6K
por: Den Hartogh, Danja J., et al.
Publicado: (2020) -
4-Phenylbutyric acid improves free fatty acid-induced hepatic insulin resistance in vivo
por: Pereira, Sandra, et al.
Publicado: (2021) -
Leptin regulates MMP-2, TIMP-1 and collagen synthesis via p38 MAPK in HL-1 murine cardiomyocytes
por: Schram, Kristin, et al.
Publicado: (2010) -
The influence of JNK and P38 MAPK inhibition on IL-12P40 and IL-23 production depending on IL12B promoter polymorphism
por: Dobreva, Zlatka Georgieva, et al.
Publicado: (2009) -
IPMK modulates FFA-induced insulin resistance in primary mouse hepatocytes
por: Jung, Ik-Rak, et al.
Publicado: (2023)