Cargando…
Progress in methods for rare variant association
Empirical studies and evolutionary theory support a role for rare variants in the etiology of complex traits. Given this motivation and increasing affordability of whole-exome and whole-genome sequencing, methods for rare variant association have been an active area of research for the past decade....
Autores principales: | Santorico, Stephanie A., Hendricks, Audrey E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895384/ https://www.ncbi.nlm.nih.gov/pubmed/26866487 http://dx.doi.org/10.1186/s12863-015-0316-7 |
Ejemplares similares
-
Comparison of statistical approaches to rare variant analysis for quantitative traits
por: Chen, Han, et al.
Publicado: (2011) -
Use of admixture and association for detection of quantitative trait loci in the Type 2 Diabetes Genetic Exploration by Next-Generation Sequencing in Ethnic Samples (T2D-GENES) study
por: Yorgov, Daniel, et al.
Publicado: (2014) -
Methods for detecting associations between phenotype and aggregations of rare variants
por: Yang, Fan, et al.
Publicado: (2011) -
Family-based Bayesian collapsing method for rare-variant association study
por: He, Liang, et al.
Publicado: (2014) -
A novel statistical method for rare-variant association studies in general pedigrees
por: Zhu, Huanhuan, et al.
Publicado: (2016)