Cargando…

Effect of Screening Abdominal Ultrasound Examination on the Decision to Pursue Advanced Diagnostic Tests and Treatment in Dogs with Neurologic Disease

BACKGROUND: Abdominal ultrasound examinations (AUS) are commonly performed before advanced neurodiagnostics to screen for diseases that might affect diagnostic plans and prognosis. OBJECTIVES: Describe the type and frequency of abnormalities found by AUS in dogs presenting with a neurological condit...

Descripción completa

Detalles Bibliográficos
Autores principales: Tong, N.M., Zwingenberger, A.L., Blair, W.H., Taylor, S.L., Chen, R.X., Sturges, B.K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895405/
https://www.ncbi.nlm.nih.gov/pubmed/25900766
http://dx.doi.org/10.1111/jvim.12602
_version_ 1782435840952107008
author Tong, N.M.
Zwingenberger, A.L.
Blair, W.H.
Taylor, S.L.
Chen, R.X.
Sturges, B.K.
author_facet Tong, N.M.
Zwingenberger, A.L.
Blair, W.H.
Taylor, S.L.
Chen, R.X.
Sturges, B.K.
author_sort Tong, N.M.
collection PubMed
description BACKGROUND: Abdominal ultrasound examinations (AUS) are commonly performed before advanced neurodiagnostics to screen for diseases that might affect diagnostic plans and prognosis. OBJECTIVES: Describe the type and frequency of abnormalities found by AUS in dogs presenting with a neurological condition, identify risk factors associated with abnormalities, and evaluate treatment decisions based on findings. ANIMALS: Seven hundred and fifty‐nine hospitalized dogs. METHODS: Retrospective study. Medical records of dogs presented from 2007 to 2009 for neurologic disease were searched for signalment, neuroanatomic localization, and AUS findings. Whether dogs had advanced neurodiagnostics and treatment was analyzed. RESULTS: Fifty‐eight percent of dogs had abnormal findings on AUS. Probability of abnormalities increased with age (P < 0.001). Nondachshund breeds had higher probability of abnormal AUS than dachshunds (odds ratio [OR] = 1.87). Eleven percent of dogs did not have advanced neurodiagnostics and in 1.3%, this was because of abnormal AUS. Dogs with ultrasonographic abnormalities were less likely than dogs without to have advanced neurodiagnostics (OR = 0.3 [95% confidence interval [CI]: 0.17, 0.52]), however, the probability of performing advanced diagnostics was high regardless of normal (OR = 0.95 [95% CI: 0.92, 0.97]) or abnormal (OR = 0.85 [95% CI: 0.81, 0.88]) AUS. Treatment was more often pursued in small dogs and less often in dogs with brain disease. CONCLUSIONS AND CLINICAL IMPORTANCE: Findings from screening AUS had a small negative effect on the likelihood of pursuing advanced neurodiagnostics. Although it should be included in the extracranial diagnostic workup in dogs with significant history or physical examination abnormalities, AUS is considered a low‐yield diagnostic test in young dogs and dachshunds.
format Online
Article
Text
id pubmed-4895405
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher John Wiley and Sons Inc.
record_format MEDLINE/PubMed
spelling pubmed-48954052016-06-22 Effect of Screening Abdominal Ultrasound Examination on the Decision to Pursue Advanced Diagnostic Tests and Treatment in Dogs with Neurologic Disease Tong, N.M. Zwingenberger, A.L. Blair, W.H. Taylor, S.L. Chen, R.X. Sturges, B.K. J Vet Intern Med Standard Articles BACKGROUND: Abdominal ultrasound examinations (AUS) are commonly performed before advanced neurodiagnostics to screen for diseases that might affect diagnostic plans and prognosis. OBJECTIVES: Describe the type and frequency of abnormalities found by AUS in dogs presenting with a neurological condition, identify risk factors associated with abnormalities, and evaluate treatment decisions based on findings. ANIMALS: Seven hundred and fifty‐nine hospitalized dogs. METHODS: Retrospective study. Medical records of dogs presented from 2007 to 2009 for neurologic disease were searched for signalment, neuroanatomic localization, and AUS findings. Whether dogs had advanced neurodiagnostics and treatment was analyzed. RESULTS: Fifty‐eight percent of dogs had abnormal findings on AUS. Probability of abnormalities increased with age (P < 0.001). Nondachshund breeds had higher probability of abnormal AUS than dachshunds (odds ratio [OR] = 1.87). Eleven percent of dogs did not have advanced neurodiagnostics and in 1.3%, this was because of abnormal AUS. Dogs with ultrasonographic abnormalities were less likely than dogs without to have advanced neurodiagnostics (OR = 0.3 [95% confidence interval [CI]: 0.17, 0.52]), however, the probability of performing advanced diagnostics was high regardless of normal (OR = 0.95 [95% CI: 0.92, 0.97]) or abnormal (OR = 0.85 [95% CI: 0.81, 0.88]) AUS. Treatment was more often pursued in small dogs and less often in dogs with brain disease. CONCLUSIONS AND CLINICAL IMPORTANCE: Findings from screening AUS had a small negative effect on the likelihood of pursuing advanced neurodiagnostics. Although it should be included in the extracranial diagnostic workup in dogs with significant history or physical examination abnormalities, AUS is considered a low‐yield diagnostic test in young dogs and dachshunds. John Wiley and Sons Inc. 2015-04-21 2015 /pmc/articles/PMC4895405/ /pubmed/25900766 http://dx.doi.org/10.1111/jvim.12602 Text en Copyright © 2015 The Authors. Journal of Veterinary Internal Medicine published by Wiley Periodicals, Inc. on behalf of the American College of Veterinary Internal Medicine. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial (http://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Standard Articles
Tong, N.M.
Zwingenberger, A.L.
Blair, W.H.
Taylor, S.L.
Chen, R.X.
Sturges, B.K.
Effect of Screening Abdominal Ultrasound Examination on the Decision to Pursue Advanced Diagnostic Tests and Treatment in Dogs with Neurologic Disease
title Effect of Screening Abdominal Ultrasound Examination on the Decision to Pursue Advanced Diagnostic Tests and Treatment in Dogs with Neurologic Disease
title_full Effect of Screening Abdominal Ultrasound Examination on the Decision to Pursue Advanced Diagnostic Tests and Treatment in Dogs with Neurologic Disease
title_fullStr Effect of Screening Abdominal Ultrasound Examination on the Decision to Pursue Advanced Diagnostic Tests and Treatment in Dogs with Neurologic Disease
title_full_unstemmed Effect of Screening Abdominal Ultrasound Examination on the Decision to Pursue Advanced Diagnostic Tests and Treatment in Dogs with Neurologic Disease
title_short Effect of Screening Abdominal Ultrasound Examination on the Decision to Pursue Advanced Diagnostic Tests and Treatment in Dogs with Neurologic Disease
title_sort effect of screening abdominal ultrasound examination on the decision to pursue advanced diagnostic tests and treatment in dogs with neurologic disease
topic Standard Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895405/
https://www.ncbi.nlm.nih.gov/pubmed/25900766
http://dx.doi.org/10.1111/jvim.12602
work_keys_str_mv AT tongnm effectofscreeningabdominalultrasoundexaminationonthedecisiontopursueadvanceddiagnostictestsandtreatmentindogswithneurologicdisease
AT zwingenbergeral effectofscreeningabdominalultrasoundexaminationonthedecisiontopursueadvanceddiagnostictestsandtreatmentindogswithneurologicdisease
AT blairwh effectofscreeningabdominalultrasoundexaminationonthedecisiontopursueadvanceddiagnostictestsandtreatmentindogswithneurologicdisease
AT taylorsl effectofscreeningabdominalultrasoundexaminationonthedecisiontopursueadvanceddiagnostictestsandtreatmentindogswithneurologicdisease
AT chenrx effectofscreeningabdominalultrasoundexaminationonthedecisiontopursueadvanceddiagnostictestsandtreatmentindogswithneurologicdisease
AT sturgesbk effectofscreeningabdominalultrasoundexaminationonthedecisiontopursueadvanceddiagnostictestsandtreatmentindogswithneurologicdisease