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A simple two-state protein unfolds mechanically via multiple heterogeneous pathways at single-molecule resolution
A major drive in protein folding has been to develop experimental technologies to resolve the myriads of microscopic pathways and complex mechanisms that purportedly underlie simple two-state folding behaviour. This is key for cross-validating predictions from theory and modern computer simulations....
Autores principales: | Schönfelder, Jörg, Perez-Jimenez, Raul, Muñoz, Victor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4895439/ https://www.ncbi.nlm.nih.gov/pubmed/27248054 http://dx.doi.org/10.1038/ncomms11777 |
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